Description

Carbamic Acid, n-[2-[2-(Aminooxy)Ethoxy]Ethoxy]-, 9H-Fluoren-9-Ylmethyl Ester is a specialized, high-purity chemical building block designed for advanced organic synthesis and bioconjugation. This compound is valued for its unique bifunctional linker properties, enabling the precise and stable attachment of molecules under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for the development of novel therapeutics and analytical tools.

Application

• Peptide and Protein Conjugation: Acts as a heterobifunctional crosslinker for attaching aminooxy-containing molecules to amine groups, facilitating the creation of stable protein-drug conjugates or antibody-oligonucleotide hybrids.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a key reagent for the introduction of aminooxy functionality into peptide chains, enabling subsequent chemoselective ligation (oxime formation) for complex biomolecule assembly.
• Bioconjugation and Labeling: Used to attach fluorescent dyes, biotin, or other reporter molecules to antibodies, enzymes, or nanoparticles for applications in diagnostics, imaging, and assay development.
• Polymer and Material Science: Functions as a functional monomer or crosslinking agent for synthesizing smart polymers, hydrogels, or surface coatings with reactive aminooxy groups.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes or affinity tags to study enzyme function and protein-protein interactions within biological systems.
• Glycoconjugate Synthesis: Facilitates the site-specific conjugation of carbohydrates to proteins or other carriers, which is critical for vaccine development and glycobiology research.

Basic Information

Product Name	Carbamic Acid, n-[2-[2-(Aminooxy)Ethoxy]Ethoxy]-, 9H-Fluoren-9-Ylmethyl Ester
CAS No.	190249-87-7
Molecular Formula	C21H24N2O6
Molecular Weight	400.43 g/mol
Synonyms	Fmoc-aminooxy-PEG2-acid; N-(2-(2-(Aminooxy)ethoxy)ethoxy)carbonyl-9-fluorenylmethyl ester; Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-Aoa(tBu)-OH (deprotected form); 9-Fluorenylmethyl N-[2-[2-(aminooxy)ethoxy]ethoxy]carbamate; Aminooxy-PEG2-acid Fmoc ester; AOA-PEG2-Fmoc; Heterobifunctional PEG linker Fmoc-Aoa
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[2-[2-(Aminooxy)Ethoxy]Ethoxy]-, 9H-Fluoren-9-Ylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, Acetonitrile; Slightly soluble in Dichloromethane

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.