Description

(2'-Naphthyl)Methyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is a sophisticated, fully protected glycosyl donor derivative, specifically engineered for complex carbohydrate synthesis. This compound matters because it provides a stable, reactive intermediate crucial for the precise construction of N-acetylglucosamine-containing oligosaccharides and glycoconjugates under controlled conditions. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel glycotherapeutics, diagnostic tools, and as a key building block in glycoscience research.

Application

• Glycoconjugate Synthesis: A critical building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
• Pharmaceutical Intermediates: Used in the research and development of new glycosidase inhibitors, anti-cancer agents, and anti-inflammatory drugs.
• Carbohydrate Chemistry Research: Serves as a protected glycosyl donor in academic and industrial laboratories studying glycosylation mechanisms and carbohydrate-protein interactions.
• Diagnostic Reagent Development: Employed in creating labeled probes and standards for assays targeting specific carbohydrate structures.
• Glycomimetics Production: Acts as a precursor for synthesizing stable glycomimetics used in drug discovery and vaccine development.
• Bioconjugation: Facilitates the site-specific attachment of carbohydrate motifs to proteins, peptides, or surfaces for various biotechnological applications.

Basic Information

Product Name	(2'-Naphthyl)Methyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside
CAS No.	190181-66-9
Molecular Formula	C26H29NO9
Molecular Weight	499.51 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose; NAP-β-GlcNAc(OAc)3; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose (2-naphthylmethyl glycoside); 2-Naphthylmethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; β-D-Glucopyranoside, 2-(acetylamino)-2-deoxy-, 2-naphthalenemethyl 3,4,6-triacetate; Protected N-Acetylglucosamine donor; GlcNAc(β)-O-(2-Nap) derivative
EINECS	Contact for details

Quality Control

Our (2'-Naphthyl)Methyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture uptake and decomposition. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-15° to -25° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.