Description

C6 L-Threo Ceramide (D18:1/6:0) is a high-purity, synthetic sphingolipid essential for advanced biomedical and cosmetic research. This specific ceramide, with its defined C6 fatty acid chain and L-threo stereochemistry, is critical for studying and modulating cellular membrane structure, signaling pathways, and skin barrier function. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of premium skincare formulations requiring precise molecular tools for efficacy and mechanism-of-action studies.

Application

• Biomedical Research: As a key reagent for studying sphingolipid metabolism, apoptosis, and cell signaling pathways in academic and pharmaceutical R&D.
• Cosmetic Science: A vital active ingredient in high-end skincare products aimed at restoring the skin's lipid barrier, improving hydration, and reducing signs of aging.
• Lipidomics & Analytical Standards: Serves as a critical reference standard for mass spectrometry-based lipid profiling and quantification in diagnostic and research laboratories.
• Drug Delivery Systems: Used in the development of liposomal and nanoparticle formulations to enhance drug solubility, stability, and targeted delivery.
• Cell Culture & Model Membranes: Incorporated into artificial membrane systems (e.g., liposomes, bilayers) to study membrane fluidity, protein interactions, and transport mechanisms.

Basic Information

Product Name	C6 L-Threo Ceramide (D18:1/6:0)
CAS No.	189894-80-2
Molecular Formula	C42H83NO4
Molecular Weight	666.12 g/mol
Synonyms	N-Hexanoyl-D-erythro-sphingosine; N-Caproyl-D-erythro-sphingosine; N-(Hexanoyl)-sphing-4-enine; Ceramide (d18:1/6:0); Ceramide NS (6:0); L-threo-C6-Ceramide; N-C6:0-Ceramide (d18:1); (2S,3R,4E)-2-Hexanamidooctadec-4-ene-1,3-diol
EINECS	Contact for details

Quality Control

Our C6 L-Threo Ceramide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide full traceability and detailed Certificates of Analysis (COA) to ensure compliance with research and development standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (Mass)	Conforms (M+Na)+
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.