Description

4-Amino-7-Trifluoromethyl-2-Phenylquinoline is a high-value, multi-functional heterocyclic building block characterized by its quinoline core substituted with amino, trifluoromethyl, and phenyl groups. This unique molecular architecture makes it a critical intermediate for advanced research and development in life sciences. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active compounds, leveraging its structural complexity to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targets in oncology, CNS disorders, and infectious diseases.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioavailability and stability.
• Material Science: Serves as an organic building block for creating advanced functional materials, such as organic light-emitting diodes (OLEDs) and charge-transport layers.
• Chemical Biology Probe Development: Utilized as a scaffold for designing fluorescent tags or molecular probes to study biological processes and enzyme functions.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and CROs (Contract Research Organizations) exploring novel heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	4-Amino-7-Trifluoromethyl-2-Phenylquinoline
CAS No.	189877-83-6
Molecular Formula	C₁₆H₁₁F₃N₂
Molecular Weight	288.27 g/mol
Synonyms	2-Phenyl-4-amino-7-trifluoromethylquinoline; 7-(Trifluoromethyl)-2-phenylquinolin-4-amine; 4-Amino-2-phenyl-7-(trifluoromethyl)quinoline; 4-Amino-7-trifluoromethyl-2-phenyl-quinoline; ATFQ; 189877-83-6; Quinoline, 4-amino-7-(trifluoromethyl)-2-phenyl-
EINECS	Contact for details

Quality Control

Our 4-Amino-7-Trifluoromethyl-2-Phenylquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.