Description

4-Chloro-7-Methoxy-2-Phenylquinoline is a high-purity, functionalized quinoline derivative that serves as a critical advanced intermediate in organic synthesis. Its value lies in its unique molecular scaffold, which combines halogen, methoxy, and phenyl substituents to enable precise structural modifications for creating novel compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinoline core for biological activity.
• Material Science Precursor: Serves as an organic precursor for the development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport layers.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and coordination chemistry.
• Fluorescent Probe Development: The quinoline structure can be functionalized further to create dyes and fluorescent markers for biochemical sensing and imaging.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Chloro-7-Methoxy-2-Phenylquinoline
CAS No.	189816-05-5
Molecular Formula	C₁₆H₁₂ClNO
Molecular Weight	269.73 g/mol
Synonyms	2-Phenyl-4-chloro-7-methoxyquinoline; 4-Chloro-7-methoxy-2-phenylquinoline; 7-Methoxy-4-chloro-2-phenylquinoline; 4-Chloro-2-phenyl-7-methoxyquinoline; 2-Phenyl-7-methoxy-4-chloroquinoline; 4-Chloro-7-methoxy-2-phenyl-quinoline; Quinoline, 4-chloro-7-methoxy-2-phenyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Methoxy-2-Phenylquinoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.