Description

α-Tetralone-13C6 CAS NO 189811-58-3 is a stable isotope-labeled analog of α-tetralone, where six carbon atoms are replaced with the carbon-13 isotope. This compound is of critical importance as a high-purity internal standard and reference material for quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and contract research organizations (CROs) engaged in method development, pharmacokinetic studies, and metabolic pathway analysis.

Application

• Quantitative Mass Spectrometry (MS): Serves as a crucial internal standard for the accurate quantification of α-tetralone and related compounds in complex biological matrices, eliminating signal variability.
• Metabolite Tracing & Pharmacokinetics: Used in drug metabolism and disposition (DMPK) studies to trace the metabolic fate of pharmaceutical compounds and calculate precise pharmacokinetic parameters.
• NMR Spectroscopy Reference: Provides a definitive chemical shift reference in 13C NMR studies for structural elucidation and reaction monitoring in synthetic chemistry.
• Analytical Method Development & Validation: Essential for developing and validating robust, regulatory-compliant (e.g., FDA, EMA) analytical methods in pharmaceutical quality control.
• Isotope Dilution Analysis: Employed in high-accuracy analytical techniques to achieve superior precision and accuracy in concentration measurements.
• Organic Synthesis Research: Acts as a labeled building block for synthesizing more complex 13C-labeled intermediates for advanced research applications.

Basic Information

Product Name	α-Tetralone-13C6
CAS No.	189811-58-3
Molecular Formula	C413C6H10O
Molecular Weight	~154.16 g/mol
Synonyms	1-Tetralone-13C6; α-Tetralone-13C6; 3,4-Dihydro-1(2H)-naphthalenone-13C6; 1-Oxo-1,2,3,4-tetrahydronaphthalene-13C6; 3,4-Dihydronaphthalen-1(2H)-one-13C6; Isotopically Labeled α-Tetralone; Carbon-13 Labeled α-Tetralone; Tetral-1-one-13C6
EINECS	Contact for details

Quality Control

Every batch of α-Tetralone-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, verified by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, isotopic abundance, and solvent residue levels to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (GC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.