Description

5-Chloro-2,6-Dimethoxy-4-Methyl-8-Nitroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, specialty dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial, anticancer, and antimalarial agents.
• Agrochemical Research: Used as a core structure for developing new pesticides, herbicides, and fungicides with targeted activity.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Dye & Pigment Synthesis: Acts as an intermediate for producing specialized nitro- and amino-quinoline dyes with specific coloristic and fastness properties.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Industrial R&D: A versatile starting material for methodological studies in organic chemistry and scale-up process optimization.

Basic Information

Product Name	5-Chloro-2,6-Dimethoxy-4-Methyl-8-Nitroquinoline
CAS No.	189746-21-2
Molecular Formula	C₁₂H₁₁ClN₂O₄
Molecular Weight	282.68 g/mol
Synonyms	8-Nitro-5-chloro-2,6-dimethoxy-4-methylquinoline; 5-Chloro-2,6-dimethoxy-4-methyl-8-nitroquinoline; 4-Methyl-5-chloro-2,6-dimethoxy-8-nitroquinoline; Quinoline, 5-chloro-2,6-dimethoxy-4-methyl-8-nitro-; 189746-21-2; 5-Chloro-4-methyl-2,6-dimethoxy-8-nitroquinoline
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 5-Chloro-2,6-Dimethoxy-4-Methyl-8-Nitroquinoline is analyzed using advanced techniques like HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.