Description

(2R,3R,4S,5R,6S)-3,4,6-Trihydroxy-2-Hydroxymethyl-7,9-Diaza-1-Oxa-Spiro[4,5]Decane-10-One-8-Thione is a sophisticated spirocyclic compound featuring a unique heterocyclic structure with multiple functional groups. This molecule is of significant interest in advanced pharmaceutical research and development, particularly as a key chiral intermediate or a potential pharmacophore for novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for use in synthetic routes and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a scaffold or precursor in medicinal chemistry for developing new drug candidates, particularly targeting enzymes or receptors.
• Biochemical Research: Potential application as a substrate or inhibitor in enzymatic studies due to its specific stereochemistry and functional groups.
• Fine Chemical Synthesis: Employed in the preparation of other high-value, specialized organic compounds for research purposes.
• Process Chemistry Development: Utilized for optimizing synthetic pathways and scaling up production of target molecules in a GMP or non-GMP environment.

Basic Information

Product Name	(2R,3R,4S,5R,6S)-3,4,6-Trihydroxy-2-Hydroxymethyl-7,9-Diaza-1-Oxa-Spiro[4,5]Decane-10-One-8-Thione
CAS No.	189633-62-3
Molecular Formula	C8H12N2O5S
Molecular Weight	248.26 g/mol
Synonyms	7,9-Diaza-1-oxaspiro[4.5]decane-10-one-8-thione, 3,4,6-trihydroxy-2-(hydroxymethyl)-, (2R,3R,4S,5R,6S)-; Spirocyclic thiohydantoin derivative; (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-7,9-diaza-1-oxaspiro[4.5]decane-3,4,6-triol-10-one-8-thione; CAS 189633-62-3.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity specifications suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Specifications can be developed to align with customer-specific requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.