Description

1,7-Dioxaspiro5.5Undecane-3,5-Diol, (3.Alpha.,5.Alpha.,6.Beta.)- CAS NO 189508-47-2 is a high-purity, stereochemically defined spirocyclic diol compound. This specialized intermediate is valued for its unique rigid molecular framework and dual hydroxyl functionality, which are critical for synthesizing complex molecules with precise spatial orientation. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spiro structure can contribute to improved biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Advanced Material Research: Incorporated into polymers and specialty chemicals to impart rigidity and specific functional group interactions, useful for creating high-performance resins or coatings.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex, musky, or woody odorants due to its spirocyclic backbone.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-forming reactions and stereoselective transformations.

Basic Information

Product Name	1,7-Dioxaspiro5.5Undecane-3,5-Diol, (3.Alpha.,5.Alpha.,6.Beta.)-
CAS No.	189508-47-2
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(3α,5α,6β)-1,7-Dioxaspiro[5.5]undecane-3,5-diol; (3alpha,5alpha,6beta)-1,7-Dioxaspiro[5.5]undecane-3,5-diol; 1,7-Dioxaspiro[5.5]undecane-3,5-diol, (3α,5α,6β)-; Spirocyclic Diol Intermediate; 189508-47-2; (3R,5R,6S)-1,7-Dioxaspiro[5.5]undecane-3,5-diol
EINECS	Contact for details

Quality Control

Our production of 1,7-Dioxaspiro5.5Undecane-3,5-Diol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.