Description

tert-Butyl 2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic molecular architecture. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other bioactive molecules. Our supply is characterized by stringent quality control, ensuring batch-to-batch consistency for reliable and reproducible synthesis outcomes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs) with spirocyclic cores.
• Chemical Biology Probes: Serves as a starting material for creating specialized molecular probes to study biological systems and enzyme functions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high-complexity intermediates.
• Academic Research: Supports investigative studies in organic synthesis methodology and the exploration of new chemical spaces in university and institutional labs.

Basic Information

Product Name	tert-Butyl 2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate
CAS No.	189320-53-4
Molecular Formula	C18H24N2O2
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-2',4'-dihydro-1'H-spiro[piperidine-3,3'-quinoline]; tert-Butyl 2,4-dihydrospiro[piperidine-3,3'-quinoline]-1-carboxylate; 1-(tert-Butoxycarbonyl)-2',4'-dihydro-1'H-spiro[piperidine-3,3'-quinoline]; Spiro[piperidine-3,3'-quinoline]-1-carboxylic acid, 2',4'-dihydro-, 1,1-dimethylethyl ester; 189320-53-4; Boc-spiro[piperidine-3,3'-quinoline]; 1-N-Boc-2',4'-dihydrospiro[piperidine-3,3'-quinoline]
EINECS	Contact for details

Quality Control

Our tert-Butyl 2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.