Description

4'-Chloro-5-Fluoro-1,1'-Biphenyl-2-Amine is a high-purity biphenyl amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated biphenyl core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a standard or reagent in method development, catalysis studies, and structure-activity relationship (SAR) exploration.
• Dye and Pigment Intermediate: Functions as a starting material for synthesizing specialized azo dyes and high-performance pigments.

Basic Information

Product Name	4'-Chloro-5-Fluoro-1,1'-Biphenyl-2-Amine
CAS No.	188731-34-2
Molecular Formula	C12H9ClFN
Molecular Weight	221.66 g/mol
Synonyms	2-Amino-4'-chloro-5-fluorobiphenyl; 4'-Chloro-5-fluoro[1,1'-biphenyl]-2-amine; 4-Chloro-5-fluorobiphenyl-2-ylamine; (4-Chloro-5-fluorobiphenyl-2-yl)amine; 2-Biphenylamine, 4'-chloro-5-fluoro-; 4'-Chloro-5-fluoro-2-aminobiphenyl
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Fluoro-1,1'-Biphenyl-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.