Description

Ruthenium Tosyl Dpen CAS NO 188444-42-0 is a highly specialized organometallic complex, specifically a ruthenium-based chiral ligand, designed for asymmetric synthesis. This compound is critically important for its role as a catalyst in enantioselective hydrogenation and other key carbon-carbon bond-forming reactions, enabling the production of single-isomer pharmaceutical intermediates and fine chemicals. It is an essential material for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity, reliable catalysts for complex synthetic pathways.

Application

• As a precursor or catalyst in asymmetric hydrogenation reactions for the synthesis of chiral amines, amino acids, and alcohols.
• Enabling enantioselective synthesis of key pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Catalytic applications in academic and industrial research for developing new synthetic methodologies.
• Use in the production of specialty chemicals and agrochemicals requiring high stereochemical purity.
• As a ligand or catalyst component in other transition metal-catalyzed transformations, such as transfer hydrogenation.
• Supporting process development and scale-up in GMP-compliant manufacturing environments for regulated substances.

Basic Information

Product Name	Ruthenium Tosyl Dpen
CAS No.	188444-42-0
Molecular Formula	C31H32N2O2RuS
Molecular Weight	603.72 g/mol
Synonyms	Ru-TsDPEN; Dichloro(p-cymene)ruthenium(II) dimer with (1R,2R)-(-)-1,2-Diphenylethylenediamine N-tosyl derivative; (R,R)-TsDPEN-Ru(II)-p-cymene complex; (1R,2R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine ruthenium complex; [RuCl(p-cymene)((R,R)-TsDPEN)]; Asymmetric hydrogenation catalyst Ru-TsDPEN; N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine, (R,R)-, ruthenium complex
EINECS	Contact for details

Quality Control

Our Ruthenium Tosyl Dpen is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical testing, including assay by HPLC, chiral purity determination, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maintain stability and prevent decomposition. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.