Description

6,7,8-Trifluoro-1,4-Dihydrogen-4-Oxo-Quinoline-3-Carboxylate Ethyl Ester is a high-purity fluorinated quinoline derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of antibacterial and anticancer agents. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to drive innovation in drug discovery pipelines, ensuring the integrity of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel fluoroquinolone antibiotics and other bioactive quinoline-based compounds.
• Antibacterial Agent Research: Serves as a core scaffold in medicinal chemistry for developing next-generation antibacterial drugs with improved efficacy.
• Oncology Drug Discovery: Used in research programs targeting the development of anticancer therapeutics due to the quinoline pharmacophore.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic systems in academic and industrial laboratories.
• Material Science Research: Investigated for potential applications in creating specialty chemicals and functional materials with unique fluorinated properties.

Basic Information

Product Name	6,7,8-Trifluoro-1,4-Dihydrogen-4-Oxo-Quinoline-3-Carboxylate Ethyl Ester
CAS No.	188432-34-0
Molecular Formula	C₁₂H₈F₃NO₃
Molecular Weight	271.19 g/mol
Synonyms	Ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 6,7,8-Trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 1,4-Dihydro-6,7,8-trifluoro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic Acid, 1,4-dihydro-6,7,8-trifluoro-4-oxo-, Ethyl Ester; Ethyl 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 188432-34-0; 6,7,8-Trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 6,7,8-Trifluoro-1,4-Dihydrogen-4-Oxo-Quinoline-3-Carboxylate Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.