Description

tert-Butyl Methyl(Piperidin-4-Yl)Carbamate Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine-carbamate structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents. The hydrochloride salt form enhances its stability and handling properties for synthetic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• API Synthesis: Serves as a critical precursor in the multi-step manufacturing process of final active pharmaceutical ingredients.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Item	Detail
Product Name	tert-Butyl Methyl(Piperidin-4-Yl)Carbamate Hydrochloride
CAS No.	188174-17-6
Molecular Formula	C12H24N2O2 • HCl
Molecular Weight	264.79 g/mol
Synonyms	1-Boc-4-(N-Methylamino)piperidine Hydrochloride; tert-Butyl 4-(Methylamino)piperidine-1-carboxylate Hydrochloride; 4-(N-Methylamino)-1-Boc-piperidine HCl; N-Boc-N-Methyl-4-aminopiperidine Hydrochloride; 1-(tert-Butoxycarbonyl)-4-(methylamino)piperidine Hydrochloride; N-Methyl-4-amino-1-Boc-piperidine HCl; 4-(Methylamino)piperidine-1-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl Methyl(Piperidin-4-Yl)Carbamate Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our analytical methods, including HPLC, NMR, and mass spectrometry, are validated to provide reliable data for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.