Description

4-(Iodomethyl)Phenol is a versatile halogenated phenolic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive iodomethyl group and a phenolic hydroxyl, makes it a valuable building block for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce functionalized phenolic units into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring phenolic ether or alkylated phenol motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators where the iodomethyl group facilitates further coupling reactions.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Polymer Modification: Employed to introduce phenolic functionalities into polymer backbones or as a cross-linking agent for specialty resins.
• Organic Synthesis Building Block: Utilized in Suzuki, Stille, and other cross-coupling reactions due to the reactive carbon-iodine bond.
• Material Science Research: Investigated for creating novel organic frameworks and functional surfaces with specific chemical properties.

Basic Information

Product Name	4-(Iodomethyl)Phenol
CAS No.	188128-71-4
Molecular Formula	C7H7IO
Molecular Weight	234.04 g/mol
Synonyms	4-(Hydroxyphenyl)methyl iodide; p-(Iodomethyl)phenol; (4-Hydroxybenzyl) iodide; 4-Hydroxybenzyl iodide; Phenol, 4-(iodomethyl)-; 1-Iodo-4-(hydroxymethyl)benzene (tautomeric form); p-Hydroxybenzyl iodide
EINECS	Contact for details

Quality Control

Our 4-(Iodomethyl)Phenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.