Description

2-Chloro-4-Formylphenyl Trifluoromethanesulfonate is a high-value, multi-functional chemical intermediate prized for its reactive triflate and formyl groups. This compound matters for its critical role in facilitating advanced cross-coupling reactions and serving as a versatile building block in complex organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring aryl-aryl coupling.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the chloro and formyl functionalities are leveraged for further derivatization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: The trifluoromethanesulfonate (triflate) group acts as an excellent leaving group in palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other performance chemicals.

Basic Information

Product Name	2-Chloro-4-Formylphenyl Trifluoromethanesulfonate
CAS No.	188112-72-3
Molecular Formula	C9H4ClF3O4S
Molecular Weight	300.64 g/mol
Synonyms	4-Formyl-2-chlorophenyl trifluoromethanesulfonate; 2-Chloro-4-formylphenyl triflate; 2-Chloro-4-formylphenyl trifluoromethylsulfonate; (2-Chloro-4-formylphenyl) trifluoromethanesulfonate; 4-(Trifluoromethanesulfonyloxy)-3-chlorobenzaldehyde; 3-Chloro-4-(trifluoromethanesulfonyloxy)benzaldehyde; Trifluoromethanesulfonic acid 2-chloro-4-formylphenyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Formylphenyl Trifluoromethanesulfonate undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality management system is designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.