Description

4-Methyl-2-[4-(Trifluoromethoxy)Phenyl]-1,3-Thiazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethoxy-substituted thiazole core structure. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting specific biological pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in areas like kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the thiazole moiety.
• Material Science: Serves as a precursor for specialty chemicals and functional materials requiring fluorine-containing aromatic systems.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic frameworks in academic and industrial research.
• Ligand & Catalyst Development: Potential use in creating specialized ligands for catalysis due to its distinct electronic properties.

Basic Information

Product Name	4-Methyl-2-[4-(Trifluoromethoxy)Phenyl]-1,3-Thiazole-5-Carboxylic Acid
CAS No.	187998-69-2
Molecular Formula	C12H8F3NO3S
Molecular Weight	303.26 g/mol
Synonyms	5-Thiazolecarboxylic acid, 4-methyl-2-[4-(trifluoromethoxy)phenyl]-; 2-(4-Trifluoromethoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid; 4-Methyl-2-(4-trifluoromethoxyphenyl)thiazole-5-carboxylic acid; 187998-69-2; 4-Methyl-2-(4-(trifluoromethoxy)phenyl)thiazole-5-carboxylic acid; 2-(4-(Trifluoromethoxy)phenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-2-[4-(Trifluoromethoxy)Phenyl]-1,3-Thiazole-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO 9001 standards for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.