Description

3,5-Bis[2-(Boc-Amino)Ethoxy]-Benzoic Acid is a specialized, high-purity chemical building block featuring a benzoic acid core flanked by two Boc-protected aminoethoxy arms. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors for constructing novel drug candidates, peptide mimetics, and sophisticated dendrimers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting complex diseases.
• Peptidomimetics & PROTACs: Used to construct sophisticated peptide-like structures and Proteolysis-Targeting Chimeras (PROTACs) due to its orthogonal protecting groups and linker functionality.
• Dendrimer & Polymer Synthesis: Serves as a versatile monomer or branching unit for creating well-defined dendritic architectures and functional polymers.
• Bioconjugation & Linker Chemistry: The carboxylic acid group enables conjugation to other molecules, making it useful for creating drug-linker systems in antibody-drug conjugates (ADCs).
• Material Science Research: Employed in the development of novel organic frameworks and functional surfaces where precise molecular geometry is required.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein interactions.

Basic Information

Item	Detail
Product Name	3,5-Bis[2-(Boc-Amino)Ethoxy]-Benzoic Acid
CAS No.	187960-74-3
Molecular Formula	C23H36N2O8
Molecular Weight	468.54 g/mol
Synonyms	Benzoic acid, 3,5-bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-; 3,5-Bis(2-((tert-butoxycarbonyl)amino)ethoxy)benzoic acid; 3,5-Bis[2-(N-Boc-amino)ethoxy]benzoic acid; Boc-AEEA-Benzoic Acid derivative; (Boc-AEEA)2-Benzoic Acid; tert-Butyl N-[2-[3,5-bis[2-[(tert-butoxycarbonyl)amino]ethoxy]benzoyl]oxy]ethyl]carbamate precursor; AEEA(Boc)2-Benzoic Acid
EINECS	Contact for details

Quality Control

Our 3,5-Bis[2-(Boc-Amino)Ethoxy]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.