Description

Benzene, 4-Ethynyl-2-Methyl-1-Nitro- CAS NO 187869-73-4 is a specialized aromatic compound featuring a nitro group and an ethynyl moiety on a methyl-substituted benzene ring. This unique structure makes it a valuable high-purity building block for advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides due to its reactive functional groups.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in organic chemistry research for Suzuki, Sonogashira, and other cross-coupling reactions to construct complex molecules.
• Ligand & Catalyst Development: Utilized for creating novel ligands and organometallic catalysts in asymmetric synthesis.
• Academic & Industrial R&D: A critical reagent for exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	Benzene, 4-Ethynyl-2-Methyl-1-Nitro-
CAS No.	187869-73-4
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	4-Ethynyl-2-methyl-1-nitrobenzene; 2-Methyl-4-ethynylnitrobenzene; 1-Nitro-4-ethynyl-2-methylbenzene; 4-Ethynyl-2-methylnitrobenzene; 2-Methyl-1-nitro-4-ethynylbenzene; 4-Ethynyl-o-methylnitrobenzene; (4-Ethynyl-2-methylphenyl)nitrate (incorrect but common alias)
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. Our manufacturing and quality processes are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, organic solvents, and incompatible materials. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.