Description

3-(Bromomethyl)-8-Quinolinol 8-Acetate is a specialized brominated quinoline derivative that serves as a versatile synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive bromomethyl group and a protected quinolinol moiety, makes it a critical building block for constructing complex heterocyclic frameworks. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of new fungicides, herbicides, and plant growth regulators that leverage the quinoline scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic semiconductors, light-emitting materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-(Bromomethyl)-8-Quinolinol 8-Acetate
CAS No.	187334-19-6
Molecular Formula	C₁₂H₁₀BrNO₃
Molecular Weight	296.12 g/mol
Synonyms	8-Acetoxy-3-(bromomethyl)quinoline; 3-(Bromomethyl)quinolin-8-yl acetate; 8-Quinolinol, 3-(bromomethyl)-, 8-acetate; 3-Bromomethyl-8-hydroxyquinoline acetate; 8-Acetyloxy-3-(bromomethyl)quinoline; 3-(Bromomethyl)-8-quinolyl acetate; HQBA (abbreviation); Quinoline-8-ol, 3-(bromomethyl)-, acetate
EINECS	Contact for details

Quality Control

Our production of 3-(Bromomethyl)-8-Quinolinol 8-Acetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and reliability for your synthetic workflows. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the specific results for your batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.