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3'α-Galactosyl-n-Acetyllactosamine CAS NO 186766-48-3


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CAS No.:186766-48-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3'α-Galactosyl-n-Acetyllactosamine is a specialized carbohydrate derivative, a trisaccharide of significant interest in glycobiology research and development. This compound serves as a crucial intermediate and reference standard for studying carbohydrate-protein interactions, particularly those involving the α-gal epitope. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors who are developing novel therapeutics, vaccines, or diagnostic tools related to immunology and infectious diseases.

Application

  • Glycobiology Research: Used as a key intermediate and substrate in enzymatic studies and for investigating glycan biosynthesis pathways.
  • Pharmaceutical Development: Serves as a reference standard and building block for the synthesis of complex glycoconjugates and potential vaccine candidates targeting specific carbohydrate antigens.
  • Diagnostic Reagent Production: Employed in the development of immunoassays and diagnostic kits for the detection of antibodies against α-gal epitopes, relevant to certain allergic responses.
  • Enzymology Studies: Acts as a specific substrate for α-galactosidase and other glycosyltransferase enzymes to study enzyme kinetics and specificity.
  • Biochemical Tool: Utilized in cell culture and binding studies to elucidate the role of glycans in cell signaling, adhesion, and pathogen recognition.
  • Standards and Calibration: Provides a high-purity chemical standard for analytical method development and quality control in related biopharmaceutical processes.

Basic Information

Product Name 3'α-Galactosyl-n-Acetyllactosamine
CAS No. 186766-48-3
Molecular Formula C26H45NO21
Molecular Weight 683.63 g/mol
Synonyms α-Galactosyl-N-acetyllactosamine; Galα1-3Galβ1-4GlcNAc; 3'-O-α-D-Galactopyranosyl-N-acetyllactosamine; α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcNAc; Trisaccharide Galα1-3Galβ1-4GlcNAc; α-Gal Epitope Trisaccharide; Blood Group B Trisaccharide Type 2 Chain; B Type 2 Trisaccharide
EINECS Contact for details

Quality Control

Our 3'α-Galactosyl-n-Acetyllactosamine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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