Description

6-Bromo-3-Chloro-2-Fluorophenol is a halogenated phenol derivative serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its precise substitution pattern makes it a critical building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require a highly functionalized aromatic core.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogen atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated and halogenated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or functionalization agent for creating specialty polymers with enhanced flame retardancy, stability, or specific surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new coupling reactions, heterocycle formation, and structure-activity relationship (SAR) studies.
• Dye & Pigment Intermediate: Employed in the synthesis of complex halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	6-Bromo-3-Chloro-2-Fluorophenol
CAS No.	186590-40-9
Molecular Formula	C6H3BrClFO
Molecular Weight	225.44 g/mol
Synonyms	2-Fluoro-6-bromo-3-chlorophenol; 3-Chloro-2-fluoro-6-bromophenol; Phenol, 6-bromo-3-chloro-2-fluoro-; 6-Bromo-3-chloro-2-fluorophenol; 2-Bromo-5-chloro-6-fluorophenol (alternative numbering); BCFP (abbreviation); 186590-40-9 (CAS registry)
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-2-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and reliable supply for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.