Description

6-Bromo-2,3-Difluorophenol is a halogenated fluorophenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents on the phenolic ring, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorophenol moiety imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers and high-performance resins.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorinated compounds and novel synthetic methodologies.

Basic Information

Product Name	6-Bromo-2,3-Difluorophenol
CAS No.	186590-23-8
Molecular Formula	C6H3BrF2O
Molecular Weight	208.99 g/mol
Synonyms	2,3-Difluoro-6-bromophenol; 6-Bromo-2,3-difluorophenol; Phenol, 6-bromo-2,3-difluoro-; 2-Bromo-4,5-difluorophenol; 186590-23-8; 6-Br-2,3-F2-PhOH
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Difluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.