Description

2-Fluoro-5-Iodophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique structure, featuring both fluorine and iodine substituents, makes it an essential precursor for cross-coupling reactions and the development of active pharmaceutical ingredients (APIs). Key industries that rely on this high-purity intermediate include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic processes.
• Material Science Research: Employed in the development of advanced organic materials and liquid crystals.
• Cross-Coupling Reactions: Acts as a crucial substrate in Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2-Fluoro-5-Iodophenol
CAS No.	186589-89-9
Molecular Formula	C6H4FIO
Molecular Weight	237.99 g/mol
Synonyms	5-Iodo-2-fluorophenol; 2-Fluoro-5-iodo-1-hydroxybenzene; Phenol, 2-fluoro-5-iodo-; 2-Fluor-5-jodphenol (German); 2-Fluoro-5-iodophénol (French); 2-Fluoro-5-yodofenol (Spanish); FIP
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-Fluoro-5-Iodophenol is monitored through in-process controls and final release testing, which typically includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing specifications and results. Our quality system is designed to ensure batch-to-batch consistency and compliance with relevant industry standards for research and manufacturing use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 15°C and 25°C. Keep away from heat, sparks, and open flame. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.