Description

Phenol, 5-Chloro-2-Fluoro- (9Ci) is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable fluorinated building block for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring a fluorophenol moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro substitution pattern confers specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic and display materials.
• Polymer Modification: Employed to introduce halogenated phenolic groups into polymer chains to alter thermal stability, solubility, or reactivity.
• Organic Synthesis Reagent: Acts as a versatile substrate for further functionalization via coupling reactions, nucleophilic substitutions, and other transformations in fine chemical manufacturing.
• Chemical Research: Used in academic and industrial laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Phenol, 5-Chloro-2-Fluoro- (9Ci)
CAS No.	186589-76-4
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	5-Chloro-2-fluorophenol; 2-Fluoro-5-chlorophenol; 5-Chloro-2-fluoro-1-hydroxybenzene; 1-Hydroxy-5-chloro-2-fluorobenzene; Phenol, 5-chloro-2-fluoro-; 186589-76-4 (CAS); 5-Chloro-2-fluorophenol (primary synonym)
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-fluorophenol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP compliance for applications requiring it.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.