Description

6-Bromo-3-(Dimethylamino)-1,2,3,4-Tetrahydro-9H-Carbazole is a high-purity, advanced pharmaceutical intermediate featuring a functionalized carbazole core. This compound matters as a critical building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers targeting the development of novel therapeutic agents, including potential central nervous system (CNS) drugs and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those with carbazole-based architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• CNS Drug Development: Serves as a scaffold for creating compounds targeting neurological disorders due to the carbazole moiety's relevance in this field.
• Kinase Inhibitor Synthesis: The bromo and dimethylamino functional groups make it a versatile starting material for constructing potential kinase inhibitor libraries.
• Organic Synthesis Building Block: Employed in academic and industrial labs for constructing complex heterocyclic systems via cross-coupling and further functionalization reactions.
• Agrochemical Research: Potential use as an intermediate in the development of new active ingredients with specific biological functions.

Basic Information

Product Name	6-Bromo-3-(Dimethylamino)-1,2,3,4-Tetrahydro-9H-Carbazole
CAS No.	186545-33-5
Molecular Formula	C14H17BrN2
Molecular Weight	293.21 g/mol
Synonyms	6-Bromo-3-(dimethylamino)-1,2,3,4-tetrahydrocarbazole; 6-Bromo-3-(N,N-dimethylamino)-1,2,3,4-tetrahydro-9H-carbazole; 9H-Carbazole, 6-bromo-3-(dimethylamino)-1,2,3,4-tetrahydro-; 3-(Dimethylamino)-6-bromo-1,2,3,4-tetrahydrocarbazole; 6-Bromo-3-dimethylamino-1,2,3,4-tetrahydro-9H-carbazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-(Dimethylamino)-1,2,3,4-Tetrahydro-9H-Carbazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.