Description

N,n-Dimethyl-D-Glucamine Hydrochloride is a high-purity, functionalized carbohydrate derivative used as a key chiral intermediate and building block in advanced chemical synthesis. This compound matters for its role in producing high-value, optically active pharmaceuticals and fine chemicals, where its specific stereochemistry is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for applications ranging from drug development to the synthesis of complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Bioconjugation Reagent: Used in the modification of biomolecules (e.g., proteins, peptides) for drug delivery systems, diagnostics, and biochemical research.
• Catalyst and Ligand Synthesis: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Glycochemistry Research: Employed in the study and synthesis of complex carbohydrates, glycoconjugates, and glycomimetics for therapeutic and diagnostic applications.
• Surface Modification Agent: Utilized to introduce hydrophilic, chiral functional groups onto polymers or nanomaterials to alter surface properties and biocompatibility.
• Reference Standard: Provides a certified standard for quality control and analytical method development in pharmaceutical and chemical laboratories.

Basic Information

Product Name	N,n-Dimethyl-D-Glucamine Hydrochloride
CAS No.	186541-49-1
Molecular Formula	C8H20ClNO5
Molecular Weight	245.70 g/mol
Synonyms	1-Deoxy-1-(dimethylamino)-D-glucitol hydrochloride; D-Glucitol, 1-deoxy-1-(dimethylamino)-, hydrochloride; (2R,3R,4R,5S)-6-(Dimethylamino)hexane-1,2,3,4,5-pentol hydrochloride; N,N-Dimethyl-1-deoxy-1-amino-D-glucitol HCl; N-Methylglucamine derivative hydrochloride; Meglumine derivative, N,N-dimethyl-; D-Glucamine, N,N-dimethyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-D-Glucamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+20.0° to +24.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.