Description

Fmoc-(3-Aminophenyl)Acetic Acid CAS NO 186320-08-1 is a high-purity, protected amino acid derivative essential for modern peptide synthesis. This compound serves as a critical building block, enabling the precise and efficient construction of complex peptide sequences for research and development. It is primarily utilized by pharmaceutical researchers, biotech companies, and CROs engaged in drug discovery, proteomics, and the development of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled, sequential addition of amino acids, particularly for incorporating modified phenylalanine analogs.
• Peptidomimetic Drug Discovery: Used to synthesize non-natural peptide analogs with enhanced stability, bioavailability, or target specificity for therapeutic applications.
• Combinatorial Chemistry Libraries: Serves as a versatile scaffold for generating diverse arrays of compounds for high-throughput screening against biological targets.
• Bioconjugation and Labeling: The reactive amino group, after deprotection, can be used to attach fluorophores, biotin, or other functional tags to peptides.
• Research Chemical for Academia: Employed in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.
• API Intermediate Development: Acts as a potential starting material or intermediate in the synthetic pathway of more complex Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Fmoc-(3-Aminophenyl)Acetic Acid
CAS No.	186320-08-1
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminophenylacetic acid; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]phenylacetic acid; Fmoc-3-Abz-OH; Fmoc-3-Aminobenzoic acid, ω-form; (3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]phenyl)acetic acid; N-Fmoc-3-aminophenylacetic acid; Fmoc-m-aminophenylacetic acid
EINECS	Contact for details

Quality Control

Every batch of Fmoc-(3-Aminophenyl)Acetic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation, meeting the exacting standards required for peptide synthesis and pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.