Description

Lewis A Trisaccharide, Methyl Glycoside is a defined carbohydrate derivative used as a critical intermediate and reference standard in glycobiology research. This compound is essential for studying carbohydrate-protein interactions, particularly those involving selectins and other lectins. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors for the development of glycan-based therapeutics, diagnostic tools, and vaccine components.

Application

• Glycobiology Research: Serves as a key intermediate and building block for the synthesis of complex oligosaccharides and glycoconjugates.
• Pharmaceutical Development: Used in the research and development of carbohydrate-based drugs, including selectin inhibitors for anti-inflammatory applications.
• Diagnostic Reagent Production: Acts as a critical component in the manufacture of diagnostic kits for detecting specific carbohydrate-binding proteins or antibodies.
• Enzyme Substrate Studies: Employed as a substrate to study the activity and specificity of glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes.
• Vaccine Adjuvant Research: Investigated for its potential role in the design of novel vaccine adjuvants and conjugate vaccines targeting carbohydrate antigens.
• Biomaterial Functionalization: Used to functionalize surfaces and materials with specific carbohydrate motifs for cell culture, biosensing, and tissue engineering applications.
• Reference Standard: Provides a high-purity standard for analytical methods such as HPLC, MS, and NMR in quality control and method validation.

Basic Information

Product Name	Lewis A Trisaccharide, Methyl Glycoside
CAS No.	186315-40-2
Molecular Formula	C22H38O15
Molecular Weight	542.53 g/mol
Synonyms	Lea Trisaccharide Methyl Glycoside; Methyl O-α-L-fucopyranosyl-(1→4)-O-[β-D-galactopyranosyl-(1→3)]-α-D-N-acetylglucosaminide; Methyl α-L-Fucp-(1→4)-[β-D-Galp-(1→3)]-α-D-GlcpNAc; Lewis A Antigen Methyl Glycoside; Lea Trisaccharide β-Methyl Glycoside; Fucα1-4(Galβ1-3)GlcNAcα1-OMe; Galβ1-3(Fucα1-4)GlcNAcα1-OMe; 186315-40-2
EINECS	Contact for details

Quality Control

Our Lewis A Trisaccharide, Methyl Glycoside is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.