Description

6-Bromo-5-Methyl-1H-Benzo[D][1,3]Oxazin-2(4H)-One is a high-value, heterocyclic organic building block with a fused benzoxazinone core, essential for advanced synthetic chemistry. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides by providing a versatile halogenated scaffold.
• Material Science: Building block for creating novel organic electronic materials, dyes, and photoactive compounds.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	6-Bromo-5-Methyl-1H-Benzo[D][1,3]Oxazin-2(4H)-One
CAS No.	186267-76-5
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	6-Bromo-5-methyl-1,4-dihydro-2H-3,1-benzoxazin-2-one; 6-Bromo-5-methyl-2H-3,1-benzoxazine-2,4(1H)-dione; 5-Methyl-6-bromo-1H-benzo[d][1,3]oxazine-2,4-dione; 186267-76-5; Benzoxazinone, 6-bromo-5-methyl-; 6-Bromo-5-methyl-4H-benzo[d][1,3]oxazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methyl-1H-Benzo[D][1,3]Oxazin-2(4H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.