Description

1H-Cyclopenta[B]Pyridine-2,5-Dione,Hexahydro-,(4Ar,7Ar)-Rel-(9Ci) CAS NO 186247-20-1 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and bicyclic lactam structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its defined stereochemistry is essential for biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the areas of neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates and complex molecules.
• Neurological Drug Research: Used in the R&D of compounds targeting neurological pathways and receptors.
• Metabolic Disease Research: Serves as a precursor in the development of potential treatments for metabolic disorders.
• Asymmetric Synthesis: Employed in chiral pool synthesis and catalysis due to its rigid, defined stereogenic centers.
• Chemical Biology & Proteomics: Utilized as a scaffold or probe in the study of enzyme inhibition and protein-ligand interactions.
• Process Chemistry Development: Acts as a standard or reference material for scaling up and optimizing synthetic routes in pilot plants.

Basic Information

Product Name	1H-Cyclopenta[B]Pyridine-2,5-Dione,Hexahydro-,(4Ar,7Ar)-Rel-(9Ci)
CAS No.	186247-20-1
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	rel-(4aR,7aR)-Hexahydro-1H-cyclopenta[b]pyridine-2,5-dione; (4aR,7aR)-rel-Hexahydro-1H-cyclopenta[b]pyridine-2,5-dione; 1H-Cyclopenta[b]pyridine-2,5-dione, hexahydro-, (4aR,7aR)-rel-; (rel-4aR,7aR)-Octahydro-2,5-dioxocyclopenta[b]pyridine; Bicyclic Lactam Intermediate; 186247-20-1; Cyclopentapyridinedione derivative
EINECS	Contact for details

Quality Control

Our production of 1H-Cyclopenta[B]Pyridine-2,5-Dione,Hexahydro-,(4Ar,7Ar)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.