Description

3,5-Bis(Aminomethyl)Benzoic Acid Dihydrochloride is a high-purity, functionalized aromatic building block of significant interest in advanced organic synthesis. Its bifunctional nature, featuring both protected amine groups and a carboxylic acid moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for creating peptidomimetics and small molecules with specific targeting properties.
• Linker Chemistry: Used in bioconjugation and the development of antibody-drug conjugates (ADCs) due to its reactive amine and carboxylic acid functional groups.
• Polymer Science: Serves as a monomer or cross-linking agent for producing specialty polyamides, polyimides, and other high-performance polymers with enhanced thermal or mechanical properties.
• Ligand Synthesis: Employed in the preparation of chelating agents and ligands for catalysis or metal ion sequestration.
• Material Science Research: Used in the development of novel organic frameworks, coatings, and advanced materials requiring precise molecular functionality.
• Chemical Biology Probes: Acts as a building block for synthesizing probes and tags used in biochemical and cellular studies.

Basic Information

Product Name	3,5-Bis(Aminomethyl)Benzoic Acid Dihydrochloride
CAS No.	185963-32-0
Molecular Formula	C10H14N2O2 · 2HCl
Molecular Weight	279.15 g/mol (for dihydrochloride salt)
Synonyms	3,5-Bis(aminomethyl)benzoic acid hydrochloride; Benzoic acid, 3,5-bis(aminomethyl)-, dihydrochloride; 3,5-Di(aminomethyl)benzoic acid dihydrochloride; 1,3-Bis(aminomethyl)-5-carboxybenzene dihydrochloride; 5-Carboxy-1,3-benzenedimethanamine dihydrochloride; 3,5-Bis(aminomethyl)benzoic acid HCl salt; 3,5-BAMBA·2HCl
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Aminomethyl)Benzoic Acid Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.