Description

Spiro[4.4]Nonane-1-Carboxylic Acid, 7-Amino-6-Hydroxy-, [5Alpha(S*),6Beta,7Beta]- (9Ci) is a high-purity, multifunctional chiral building block of significant interest in advanced organic synthesis. Its unique spirocyclic core structure, combined with amino and carboxylic acid functional groups, makes it a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the defined spatial orientation of functional groups is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Its constrained spirocyclic structure is valuable for mimicking peptide turn motifs in medicinal chemistry programs.
• Material Science: Potential building block for specialty polymers and advanced organic materials requiring rigid, three-dimensional architectures.
• Academic & Institutional Research: Employed in synthetic methodology studies and the exploration of new chemical spaces in university and R&D laboratory settings.

Basic Information

Product Name	Spiro[4.4]Nonane-1-Carboxylic Acid, 7-Amino-6-Hydroxy-, [5Alpha(S*),6Beta,7Beta]- (9Ci)
CAS No.	185956-37-0
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	7-Amino-6-hydroxy-spiro[4.4]nonane-1-carboxylic acid; (5S*,6β,7β)-7-Amino-6-hydroxyspiro[4.4]nonane-1-carboxylic acid; 1-Carboxyspiro[4.4]nonane-7-amino-6-ol; Spiro[4.4]nonane-1-carboxylic acid, 7-amino-6-hydroxy-, (5α,6β,7β)-; 185956-37-0; Amino-hydroxy spiro[4.4]nonane carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Spiro[4.4]Nonane-1-Carboxylic Acid, 7-Amino-6-Hydroxy-, [5Alpha(S*),6Beta,7Beta]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting customer and research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.