Description

2,2',4,4',5,5'-Hexacb (Pcb-153) (13C12, 99%) 40+/-2 Ug/Ml In Nonane is a high-purity, isotopically labeled analytical reference standard, essential for precise quantification and method validation in environmental and toxicological analysis. This certified solution provides a critical benchmark for the accurate detection and measurement of persistent organic pollutants, ensuring data integrity and regulatory compliance. It is primarily required by analytical laboratories, environmental testing facilities, and research institutions engaged in food safety monitoring, ecological studies, and occupational health assessments.

Application

• Primary Standard for Calibration: Used to calibrate GC-MS, LC-MS, and other analytical instrumentation for the quantification of PCB congeners in complex matrices.
• Method Development & Validation: Serves as a critical component in establishing and verifying the accuracy, precision, and detection limits of analytical methods for persistent organic pollutants (POPs).
• Internal Standard in Isotope Dilution Mass Spectrometry (IDMS): The 13C12-labeled structure is ideal for use as an internal standard to correct for analyte loss during sample preparation and matrix effects, enhancing analytical precision.
• Environmental Monitoring: Enables the trace-level analysis of PCB-153 in soil, sediment, water, and air samples to assess contamination and track environmental remediation efforts.
• Food & Feed Safety Analysis: Employed in the testing of agricultural products, seafood, and animal feed for compliance with maximum residue limits (MRLs) set by global food safety authorities.
• Human Biomonitoring & Clinical Research: Facilitates the measurement of PCB body burden in blood, serum, or adipose tissue for epidemiological studies and health risk assessments.
• Quality Assurance/Quality Control (QA/QC): Used in proficiency testing and as a control material to ensure the ongoing reliability and comparability of laboratory test results.
• Regulatory Compliance Testing: Supports testing mandated by regulations such as the Stockholm Convention, EPA methods, and EU directives on environmental pollutants.

Basic Information

Product Name	2,2',4,4',5,5'-Hexacb (Pcb-153) (13C12, 99%) 40+/-2 Ug/Ml In Nonane
CAS No.	185376-58-3
Molecular Formula	¹³C₁₂H₄Cl₆
Molecular Weight	~373.66 (¹³C₁₂)
Synonyms	PCB 153 (13C12); 2,2',4,4',5,5'-Hexachlorobiphenyl-13C12; 2,2',4,4',5,5'-HexaCB-13C12; 2,2',4,4',5,5'-Hexachlorobiphenyl (UL-13C12); IUPAC: 1,2,3,5-tetrachloro-4-(2,4,5-trichlorophenyl)benzene-13C12; BZ# 153 (13C12); Polychlorinated Biphenyl Congener 153 (13C Labeled); [13C12]-PCB 153
EINECS	Contact for details

Quality Control

This certified reference material is produced under ISO 17034 guidelines for reference material producers. Each batch is characterized for identity, concentration, and isotopic purity using advanced techniques including GC-MS and NMR. A comprehensive Certificate of Analysis (COA) is supplied, detailing the certified concentration, associated uncertainty, expiration date, and traceability to international standards. Our quality system ensures compliance with the requirements of ISO/IEC 17025 testing laboratories.

Storage

Preserve in the original sealed vial as supplied, in a tightly closed container, protected from light. Store at 2-8°C (refrigerated). The nonane solvent is highly flammable; keep away from heat, sparks, and open flame. Store in a well-ventilated area, segregated from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (GC-MS)	Conforms to reference standard
Certified Concentration	40 ± 2 µg/mL in Nonane
Expanded Uncertainty (k=2)	As per COA
Isotopic Purity (13C12)	≥ 99%
Chemical Purity (HPLC)	≥ 99%
Solvent	Nonane (HPLC/GC Grade)
Homogeneity	Verified
Stability	Stable until expiry date when stored as directed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.