Description

Benzeneacetic Acid, α-Amino-2-Hydroxy-, (Alphar)- (9Ci) is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of pharmaceuticals, agrochemicals, and specialty fine chemicals. It is particularly valuable for research and production teams in the pharmaceutical and biotechnology sectors who require high-purity, enantiomerically pure intermediates for constructing complex molecular architectures, such as peptide mimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology, neurology, and metabolic disease research.
• Peptidomimetic Chemistry: Used to incorporate unnatural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Agrochemical Synthesis: Serves as a precursor in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Utilized as a standard or reagent in enzymatic studies and metabolic pathway analysis.
• Fine Chemical Production: Acts as a building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	Benzeneacetic Acid, α-Amino-2-Hydroxy-, (Alphar)- (9Ci)
CAS No.	185339-06-4
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	(R)-2-Amino-2-hydroxy-2-phenylacetic acid; D-2-Amino-2-hydroxy-2-phenylacetic acid; (R)-2-Hydroxy-2-phenylglycine; (R)-α-Hydroxy-α-phenylglycine; (R)-2-Phenylglycinol acid; (R)-Mandelic acid amine; (R)-Aminohydroxyphenylacetic acid; (R)-2-Amino-2-phenyllactic acid (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of Benzeneacetic Acid, α-Amino-2-Hydroxy-, (Alphar)- (9Ci) adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, chiral content, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e. (R-enantiomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.