Description

2-tert-Butoxycarbonylamino-3-(3,4-Dichloro-Phenyl)-Propionic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in the development of complex molecules, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis and medicinal chemistry for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of combinatorial libraries.
• Bioconjugation: Facilitates the site-specific modification of proteins and other biomolecules.
• Chemical Biology Probes: Integral for creating labeled peptides and probes used in biochemical assays and diagnostic research.
• Agrochemical Synthesis: Acts as an intermediate in the development of specialized agrochemicals.

Basic Information

Product Name	2-tert-Butoxycarbonylamino-3-(3,4-Dichloro-Phenyl)-Propionic Acid
CAS No.	185321-62-4
Molecular Formula	C14H17Cl2NO4
Molecular Weight	334.19 g/mol
Synonyms	Boc-3,4-dichloro-DL-phenylalanine; N-Boc-3-(3,4-dichlorophenyl)alanine; N-(tert-Butoxycarbonyl)-3-(3,4-dichlorophenyl)alanine; 2-[(tert-Butoxycarbonyl)amino]-3-(3,4-dichlorophenyl)propanoic acid; Boc-DL-3,4-dichloro-Phe-OH; (RS)-2-(tert-Butoxycarbonylamino)-3-(3,4-dichlorophenyl)propionic acid; N-Boc-3,4-dichloro-DL-phenylalanine; 3-(3,4-Dichlorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxycarbonylamino-3-(3,4-Dichloro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.