Description

n-Alloc-1 6-Hexanediamine Hydrochloride is a protected diamine derivative, specifically the hydrochloride salt of N-Alloc-1,6-hexanediamine. This compound is a crucial building block in organic synthesis, offering a reactive primary amine group protected by an allyloxycarbonyl (Alloc) group, which can be selectively deprotected under mild conditions. It is primarily used by researchers and manufacturers in the pharmaceutical, bioconjugation, and peptide synthesis sectors for the controlled introduction of amine functionalities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs) and drug candidates requiring selective amine protection strategies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a protected lysine-like side chain or as a spacer/linker molecule.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker for attaching drugs, dyes, or other functional molecules to proteins, antibodies, or nanoparticles via its amine group after deprotection.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the synthesis of specialized polyamides, polyurethanes, and functional polymers.
• Chemical Biology Probes: Utilized in the synthesis of probes and tools for studying biological processes due to its selective reactivity.
• Ligand & Catalyst Development: Acts as a precursor for creating chelating ligands or organocatalysts in asymmetric synthesis.

Basic Information

Product Name	n-Alloc-1 6-Hexanediamine Hydrochloride
CAS No.	184292-16-8
Molecular Formula	C10H21ClN2O2
Molecular Weight	236.74 g/mol
Synonyms	N-Alloc-1,6-hexanediamine hydrochloride; 1,6-Hexanediamine, N-[(allyloxy)carbonyl]-, hydrochloride (1:1); N6-Alloc-1,6-diaminohexane hydrochloride; N-Alloc-hexamethylenediamine hydrochloride; Allyl N-(6-aminohexyl)carbamate hydrochloride; (6-{[(Allyloxy)carbonyl]amino}hexyl)ammonium chloride; Alloc-HDA·HCl; Alloc-protected hexanediamine HCl
EINECS	Contact for details

Quality Control

Our n-Alloc-1 6-Hexanediamine Hydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.