Description

4-Bromo-8-Methoxynaphthalen-1-Ol is a high-purity, functionalized naphthalene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and materials science sectors. It is primarily sought by research chemists and process development scientists for applications in medicinal chemistry, agrochemical research, and the synthesis of specialty dyes and pigments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its bromo and methoxy functional groups for structure-activity relationship (SAR) studies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a core structure or a functionalization point in the synthesis of electron-transport or host materials for OLED displays and lighting.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis, including palladium-catalyzed cross-coupling reactions.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating high-performance, color-fast naphthalene-based dyes and organic pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	4-Bromo-8-Methoxynaphthalen-1-Ol
CAS No.	184221-86-1
Molecular Formula	C11H9BrO2
Molecular Weight	253.09 g/mol
Synonyms	1-Hydroxy-4-bromo-8-methoxynaphthalene; 4-Bromo-8-methoxy-1-naphthol; 8-Methoxy-4-bromo-1-naphthol; 4-Bromo-8-methoxynaphthalen-1-ol; 1-Naphthol, 4-bromo-8-methoxy-; 4-Bromo-8-methoxy-1-hydroxynaphthalene; 184221-86-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-8-Methoxynaphthalen-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be conducted under subdued lighting where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.