Description

Ethyl (R)-Piperidine-2-Carboxylate Hcl is a high-purity chiral building block essential for the synthesis of complex pharmaceutical molecules. Its value lies in providing a stereochemically defined piperidine scaffold, a core structure found in numerous bioactive compounds and active pharmaceutical ingredients (APIs). This intermediate is critically needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drugs and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) drugs, analgesics, and other therapeutic agents.
• API Synthesis: Used in the construction of piperidine-based active pharmaceutical ingredients (APIs), where the (R)-enantiomer is required for specific biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in asymmetric catalytic processes and chiral pool synthesis.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that utilize chiral piperidine motifs.
• Chemical Biology & Proteomics: Used as a building block for designing enzyme inhibitors, molecular probes, and peptide mimetics.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and custom synthesis projects in academic and industrial R&D laboratories.

Basic Information

Product Name	Ethyl (R)-Piperidine-2-Carboxylate Hcl
CAS No.	183786-20-1
Molecular Formula	C8H15NO2·HCl
Molecular Weight	193.67 g/mol (as free base: 157.21)
Synonyms	(R)-Ethyl pipecolate hydrochloride; (R)-Ethyl piperidine-2-carboxylate hydrochloride; (R)-Piperidine-2-carboxylic acid ethyl ester hydrochloride; (R)-Ethyl 2-piperidinecarboxylate HCl; (R)-2-Carbethoxypiperidine hydrochloride; (R)-Pipecolinic acid ethyl ester hydrochloride; (R)-Ethyl 2-piperidinecarboxylate monohydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl (R)-Piperidine-2-Carboxylate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.