Description

Chcc Acid (6-Chloro-7-Hydroxycoumarin-3-Carboxylic Acid) is a high-purity, functionalized coumarin derivative serving as a critical building block and analytical reagent. Its value lies in its unique molecular structure, which combines a reactive carboxylic acid group with a halogenated, hydroxylated coumarin core, enabling precise chemical modifications and fluorescence properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors, particularly for developing active pharmaceutical ingredients (APIs), fluorescent probes, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in developing compounds with coumarin-based scaffolds for therapeutic applications.
• Fluorescent Probe & Dye Synthesis: Utilized as a precursor for creating sensitive fluorescent tags and indicators used in biochemical assays, cell imaging, and diagnostic kits.
• Agrochemical Research: Serves as an intermediate in the development of new-generation pesticides and herbicides, leveraging its bioactive coumarin structure.
• Organic Electronic Materials: Acts as a building block for organic semiconductors and light-emitting materials due to its conjugated system and functional handles for polymerization.
• Chemical Biology Tool: Used in proteomics and enzyme studies as a labeling agent or as a substrate analog for investigating enzyme mechanisms.
• Cross-Coupling Reactions: The chloro substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to create diverse compound libraries.

Basic Information

Product Name	Chcc Acid (6-Chloro-7-Hydroxycoumarin-3-Carboxylic Acid)
CAS No.	183736-74-5
Molecular Formula	C10H5ClO5
Molecular Weight	240.60 g/mol
Synonyms	6-Chloro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid; 6-Chloro-7-hydroxycoumarin-3-carboxylic acid; 3-Carboxy-6-chloro-7-hydroxycoumarin; CHCC; 6-Chloro-7-hydroxy-2H-1-benzopyran-2-one-3-carboxylic acid; 183736-74-5; 6-Chloro-7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Chcc Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from strong alkalis and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.