Description

Pyrrolidine, 2-Methyl-1-Nitro-, (R)- (9Ci) is a high-purity, chiral building block of significant importance in asymmetric synthesis. Its value lies in the nitro group and the stereogenic center, which enable the construction of complex, optically active nitrogen-containing heterocycles. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a precursor for chiral pyrrolidine derivatives, which are common scaffolds in medicinal chemistry and natural product synthesis.
• Agrochemical Research: Employed in the synthesis of advanced, stereospecific pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Item	Detail
Product Name	Pyrrolidine, 2-Methyl-1-Nitro-, (R)- (9Ci)
CAS No.	183474-66-0
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(R)-2-Methyl-1-nitropyrrolidine; (R)-1-Nitro-2-methylpyrrolidine; (2R)-2-Methyl-1-nitropyrrolidine; (R)-1-Nitro-2-methylazolidine; 1-Nitro-2-methylpyrrolidine, (R)-; 2-Methyl-1-nitropyrrolidine, (R)-; (R)-2-Methyl-1-nitro-pyrrolidine; (R)-1-Nitro-2-methyl-pyrrolidine
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 2-Methyl-1-Nitro-, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.