Description

1,4,7,10-Tetraazacyclododecane, 1,4,7-Tris(Phenylmethyl)- is a functionalized cyclen derivative, a key intermediate in the synthesis of sophisticated macrocyclic chelators. This compound matters for its role as a precursor to highly selective ligands used in medical imaging, catalysis, and metal ion separation technologies. Industries requiring advanced coordination chemistry, such as pharmaceutical research, diagnostic contrast agent development, and specialty chemical manufacturing, are the primary users of this high-value intermediate.

Application

• Pharmaceutical Intermediate: Critical precursor for synthesizing MRI contrast agents (Gadolinium-based) and radiopharmaceuticals.
• Catalyst Ligand Synthesis: Used to create tailored macrocyclic ligands for homogeneous catalysis and asymmetric synthesis.
• Chemical Sensing & Separation: Building block for developing selective ionophores and extraction agents for metal recovery.
• Material Science: Functional component in the development of advanced polymers and supramolecular assemblies.
• Research & Development: Essential reagent in academic and industrial labs for exploring new coordination complexes.

Basic Information

Product Name	1,4,7,10-Tetraazacyclododecane, 1,4,7-Tris(Phenylmethyl)-
CAS No.	183160-82-9
Molecular Formula	C33H42N4
Molecular Weight	494.72 g/mol
Synonyms	1,4,7-Tris(benzyl)-1,4,7,10-tetraazacyclododecane; Tris(benzyl)cyclen; 1,4,7-Tribenzyl-1,4,7,10-tetraazacyclododecane; TBTA (context-dependent); 1,4,7-Tris(phenylmethyl)-1,4,7,10-tetraazacyclododecane; Cyclen, 1,4,7-tris(phenylmethyl)-; 1,4,7,10-Tetraazacyclododecane, 1,4,7-tris(benzyl)-
EINECS	Contact for details

Quality Control

Our 1,4,7,10-Tetraazacyclododecane, 1,4,7-Tris(Phenylmethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.