Description

Carbamic Acid, (2-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative, a versatile building block in advanced organic synthesis. Its molecular structure, featuring both a carbamate and a tert-butyl ester group, makes it a valuable intermediate for constructing complex molecules with high purity and defined stereochemistry. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as peptide mimetics and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing protease inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its carbamate functionality is integral to biological activity.
• Peptide Mimetics & PROTACs: Serves as a crucial component in the design and synthesis of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Polymer Chemistry: Acts as a monomer or chain modifier in the development of specialized polyurethanes and other functional polymers.
• Organic Synthesis Reagent: Employed as a protecting group for amines or as a coupling agent in multi-step synthetic routes under mild conditions.
• Material Science Research: Investigated for creating novel organic frameworks and coatings with specific chemical resistance or biocompatibility properties.

Basic Information

Item	Details
Product Name	Carbamic Acid, (2-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	183059-24-7
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	tert-Butyl N-(2-hydroxy-2-methylpropyl)carbamate; 2-Methyl-2-[(tert-butoxycarbonyl)amino]propan-1-ol; 1,1-Dimethylethyl N-(2-hydroxy-2-methylpropyl)carbamate; Boc-AMP-OH; (2-Hydroxy-2-methylpropyl)carbamic acid tert-butyl ester; N-Boc-2-amino-2-methyl-1-propanol; N-(tert-Butoxycarbonyl)-2-amino-2-methylpropanol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (2-Hydroxy-2-Methylpropyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.