Description

2-Amino-4-Bromo-6-Fluorophenol is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and fluoro substituents on a phenolic ring, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Building block for the synthesis of functional polymers, dyes, and advanced organic electronic materials due to its electron-donating and withdrawing groups.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	2-Amino-4-Bromo-6-Fluorophenol
CAS No.	182499-89-4
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	4-Bromo-2-amino-6-fluorophenol; 6-Fluoro-2-amino-4-bromophenol; 2-Amino-4-bromo-6-fluorophenol; Phenol, 2-amino-4-bromo-6-fluoro-; 4-Bromo-6-fluoro-2-aminophenol; 2-Amino-4-bromo-6-fluoro-1-hydroxybenzene; 1-Hydroxy-2-amino-4-bromo-6-fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Bromo-6-Fluorophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity and impurity profiles determined by validated methods including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged operations to minimize oxidation.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.