Description

4-tert-Butylthiacalix[4]arene is a functionalized macrocyclic compound belonging to the thiacalixarene family, known for its unique three-dimensional cavity structure. This molecular architecture makes it an excellent host molecule for selective ion and molecular recognition, a critical property for advanced separation and sensing technologies. It is primarily utilized by researchers and manufacturers in the fields of supramolecular chemistry, materials science, and analytical chemistry for developing novel sensors, catalysts, and extraction agents.

Application

• Ion-Selective Electrodes & Sensors: Acts as an ionophore for creating highly selective membranes to detect specific metal ions (e.g., heavy metals, alkali metals) in environmental and biological samples.
• Supramolecular Chemistry Research: Serves as a fundamental building block for constructing complex molecular assemblies, capsules, and functional materials due to its pre-organized cavity and modifiable upper/lower rims.
• Catalysis: Used as a ligand or support to create novel metal-organic complexes for catalytic applications, including oxidation and coupling reactions.
• Separation Science: Employed in the development of solid-phase extraction (SPE) materials, chromatographic stationary phases, and membrane technologies for the selective removal or concentration of target analytes.
• Pharmaceutical & Biomedical Research: Investigated for potential applications in drug delivery systems, as a carrier for bioactive molecules, or in diagnostic assays leveraging its host-guest chemistry.
• Materials Science: Incorporated into polymers, coatings, or nanomaterials to impart specific recognition properties or to create stimuli-responsive "smart" materials.

Basic Information

Product Name	4-tert-Butylthiacalix[4]arene
CAS No.	182496-55-5
Molecular Formula	C44H48O4S4
Molecular Weight	769.11 g/mol
Synonyms	p-tert-Butylthiacalix[4]arene; 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetrahydroxy-2,8,14,20-tetrathiacalix[4]arene; Thiacalix[4]arene tetra-tert-butyl derivative; TC4A-tBu; 4-tert-Butyl-2,8,14,20-tetrathia[4]calixarene; 25,26,27,28-Tetrahydroxy-5,11,17,23-tetra-tert-butyl-2,8,14,20-tetrathiacalix[4]arene
EINECS	Contact for details

Quality Control

Our 4-tert-Butylthiacalix[4]arene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.