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Hexacosanamide, n-[(1S,2R)-2-Hydroxy-1-(Hydroxymethyl)Heptadecyl]- (9C I) CAS NO 182362-38-5


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CAS No.:182362-38-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Hexacosanamide, n-[(1S,2R)-2-Hydroxy-1-(Hydroxymethyl)Heptadecyl]- (9C I) is a high-purity, synthetic ceramide analog, a critical building block in advanced lipid research and formulation. This compound is essential for developing sophisticated cosmetic and pharmaceutical delivery systems that mimic and enhance the skin's natural barrier function. It is primarily sought by R&D scientists and formulators in the personal care, dermatological, and nutraceutical industries for creating next-generation skincare actives and lipid-based nanocarriers.

Application

  • High-Performance Skincare Actives: A key synthetic precursor for formulating advanced ceramide-based moisturizers, anti-aging serums, and skin barrier repair treatments.
  • Lipid Nanoparticle (LNP) Development: Used in the research and production of novel lipid nanoparticles for targeted drug and cosmetic active delivery.
  • Biomimetic Membrane Studies: Serves as a model compound in biophysical research to study cell membrane structure, fluidity, and permeability.
  • Pharmaceutical Excipients: Employed in the development of specialized lipid excipients for enhancing the solubility and bioavailability of poorly soluble APIs.
  • Hair Care Formulations: Incorporated into premium conditioners and treatments to improve hair strength, shine, and manageability by mimicking natural lipids.
  • Cosmetic Delivery Systems: A component in the creation of liposomes, niosomes, and other vesicular systems for the sustained release of cosmetic ingredients.

Basic Information

Product Name Hexacosanamide, n-[(1S,2R)-2-Hydroxy-1-(Hydroxymethyl)Heptadecyl]- (9C I)
CAS No. 182362-38-5
Molecular Formula C44H89NO3
Molecular Weight 680.2 g/mol
Synonyms Ceramide 9C I (Synthetic); N-[(1S,2R)-2-Hydroxy-1-(hydroxymethyl)heptadecyl]hexacosanamide; (1S,2R)-N-(2-Hydroxy-1-hydroxymethylheptadecyl)hexacosanamide; Phytosphingosine-type Ceramide (C24:0/18:0); Synthetic Ceramide AP; Ceramide Type III analog; Lipid 182362-38-5; Long-chain ceramide analog
EINECS Contact for details

Quality Control

Our Hexacosanamide, n-[(1S,2R)-2-Hydroxy-1-(Hydroxymethyl)Heptadecyl]- (9C I) is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity, correct stereochemistry, and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Specific Rotation Contact for details
Loss on Drying ≤ 1.0%
Heavy Metals ≤ 10 ppm
Residual Solvents Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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