Description

E-2-Chloro-6-Methoxy-3-(2-Nitro)Vinylquinoline is a specialized quinoline derivative, a high-purity chemical intermediate of significant interest in advanced organic synthesis. Its unique molecular structure, featuring a chloro, methoxy, and nitrovinyl substituent pattern, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its quinoline core for bioactivity.
• Material Science: Serves as a monomer or dopant in the research of advanced organic electronic materials, such as OLEDs or sensors.
• Dye & Pigment Synthesis: Acts as an intermediate for creating novel quinoline-based dyes with specific light-absorption properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in cross-coupling and cyclization reactions.
• Ligand & Catalyst Development: Utilized to synthesize novel nitrogen-containing ligands for metal catalysis.

Basic Information

Product Name	E-2-Chloro-6-Methoxy-3-(2-Nitro)Vinylquinoline
CAS No.	182050-23-3
Molecular Formula	C₁₂H₉ClN₂O₃
Molecular Weight	264.66 g/mol
Synonyms	2-Chloro-6-methoxy-3-[(E)-2-nitroethenyl]quinoline; (E)-2-Chloro-6-methoxy-3-(2-nitrovinyl)quinoline; 3-[(E)-2-Nitroethenyl]-2-chloro-6-methoxyquinoline; Quinoline, 2-chloro-6-methoxy-3-[(E)-2-nitroethenyl]-; 182050-23-3; E-2-Chloro-6-methoxy-β-nitrostyrylquinoline; 2-Chloro-6-methoxy-3-(2-nitrovinyl)quinoline (E-isomer)
EINECS	Contact for details

Quality Control

Every batch of E-2-Chloro-6-Methoxy-3-(2-Nitro)Vinylquinoline is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
E-Isomer Content (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.