Description

3-Fluoro-4-(1H-1,2,4-Triazol-1-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an aniline core with fluorinated and triazole substituents. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily utilized by R&D teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents, particularly in areas like kinase inhibitors and antifungal drugs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and antifungal therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in organic and medicinal chemistry.
• Kinase Inhibitor Development: The aniline-triazole-fluorine motif is valuable for constructing potential kinase inhibitor scaffolds.
• Material Science Research: Investigated for the creation of specialty polymers and advanced functional materials.

Basic Information

Product Name	3-Fluoro-4-(1H-1,2,4-Triazol-1-Yl)Aniline
CAS No.	181997-13-7
Molecular Formula	C8H7FN4
Molecular Weight	178.17 g/mol
Synonyms	3-Fluoro-4-(1H-1,2,4-triazol-1-yl)benzenamine; 4-Amino-2-fluoro-1-(1H-1,2,4-triazol-1-yl)benzene; 1-(4-Amino-2-fluorophenyl)-1H-1,2,4-triazole; 181997-13-7; 3-Fluoro-4-(1,2,4-triazol-1-yl)aniline; Benzenamine, 3-fluoro-4-(1H-1,2,4-triazol-1-yl)-; 4-(1H-1,2,4-Triazol-1-yl)-3-fluoroaniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(1H-1,2,4-Triazol-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.