Description

5-(3-Fluorophenyl)Nicotinic Acid is a high-purity fluorinated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated phenyl ring and a pyridinecarboxylic acid moiety, enabling precise modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs for studying metabolic pathways and protein-ligand interactions.

Basic Information

Product Name	5-(3-Fluorophenyl)Nicotinic Acid
CAS No.	181705-88-4
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	3-Fluoro-5-pyridinecarboxylic acid, 3'-Fluorobiphenyl-3-carboxylic acid; 5-(3-Fluorophenyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-(3-fluorophenyl)-; Nicotinic acid, 5-(3-fluorophenyl)-; BRN 9076666
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorophenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.