Description

(1S,2S)-(+)-2-Benzyloxycyclopentylamine is a chiral amine derivative featuring a benzyl-protected hydroxyl group on a cyclopentane scaffold. This compound matters as a versatile chiral building block and intermediate in asymmetric synthesis, offering precise stereochemical control for the development of complex molecules. It is primarily needed by pharmaceutical research and fine chemical synthesis teams for creating active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in advanced pesticides and herbicides.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	(1S,2S)-(+)-2-Benzyloxycyclopentylamine
CAS No.	181657-57-8
Molecular Formula	C₁₂H₁₇NO
Molecular Weight	191.27 g/mol
Synonyms	(1S,2S)-2-(Benzyloxy)cyclopentanamine; (+)-(1S,2S)-2-Benzyloxycyclopentylamine; (1S,2S)-rel-2-(Phenylmethoxy)cyclopentanamine; Cyclopentanamine, 2-(phenylmethoxy)-, (1S,2S)-; BOCA; 2-Benzyloxycyclopentylamine (enantiomer)
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Benzyloxycyclopentylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.